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© Arne Elofsson

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1. TOPCONS2.0 dataset

Zip file for the dataset used in the paper: TOPCONS2.0_datasets.zip

Format:

  Each target contains three lines
  line 1: Sequence description
  line 2: Amino acid sequence in one letter code
  line 3: Topology and signal peptide of the protein in one letter code
          S - Signal peptide
          I - Inside of the membrane
          O - Outside of the membrane
          M - Transmembrane region
        

2. Software of TOPCONS2.0 on the github:

https://github.com/ElofssonLab/TOPCONS2

3. Run TOPCONS2 with Docker:

We have also prepared a Docker image of TOPCONS2, which can be obtained by

docker pull nanjiang/topcons2

Detailed instructions can be found at https://github.com/ElofssonLab/TOPCONS2#run-topcons2-with-docker

4. Run TOPCONS2 with Singularity

You can also run TOPCONS2 with Singularity. Obtain the Singularity image by

singularity pull docker://nanjiang/topcons2

Detailed instructions can be found at https://github.com/ElofssonLab/TOPCONS2#run-topcons2-with-singularity

5. The database for TOPCONS2.0 in one zip file.

Please note that the zip file is very large.

topcons2_database.zip (69.2 GB)

md5_checksum: 6415052cb72dc76c9463538fc2c1bca3

The database is created based on Pfam 35.0 and Uniprot KB database as of 2021_03.